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The New England Journal of Medicine: Rethinking Covid-19 Test Sensitivity — A Strategy for Containment

It’s time to change how we think about the sensitivity of testing for Covid-19. The Food and Drug Administration (FDA) and the scientific community are currently almost exclusively focused on test sensitivity, a measure of how well an individual assay can detect viral protein or RNA molecules. Critically, this measure neglects the context of how the test is being used. Yet when it comes to the broad screening the United States so desperately needs, context is fundamental. The key question is not how well molecules can be detected in a single sample but how effectively infections can be detected in a population by the repeated use of a given test as part of an overall testing strategy — the sensitivity of the testing regimen.

A regimen of regular testing works as a sort of Covid-19 filter, by identifying, isolating, and thus filtering out currently infected persons, including those who are asymptomatic. Measuring the sensitivity of a testing regimen or filter requires us to consider a test in context: how often it’s used, to whom it’s applied, when in the course of an infection it works, and whether its results are returned in time to prevent spread.1-3

Archived Briefings from Protect Our Province BC

Title image for briefing April 20 - COVID in the House: Protect Your Loved Ones
Wednesday, April 27th from 12:00-1:00 PDT What should you do if someone in your house tests positive for COVID-19? How do we prevent it from passing to loved ones in the household? Why should we care? Data is emerging that, due to variant mutations, COVID-19 reinfections are happening, even in highly-vaccinated countries. For that reason,… Continue reading COVID-19 in the House: How to Protect Your Loved Ones
Title image for Briefing 14 April 7, 2022 - COVID Doesn't Take Breaks, Neither Can We
Thursday, April 7 at 12:00 noon PDT Ignoring the 6th wave won’t stop it. What does the evidence say? Join Dr. Lyne Filiatrault, Dr. Brenda Hardie, and Gosia Gasperowicz, PhD, as they discuss what BC needs to do to lower community transmission as the most infectious strain of COVID ever becomes dominant across the globe.… Continue reading COVID-19 Doesn’t Take Breaks. Neither Can We.
Title image for Briefing 13: Ethics in Canada, March 23, 2022
Wednesday, March 23rd, 12:30-1:30 pm PT Join Canadian researcher and author Jon Parsons in a discussion with Protect our Province BC member Dr. Amy Tan about how Canada’s response to the COVID-19 pandemic amounts to a failure of ethical action.  The pandemic has brought issues with Canada’s governing systems and cultural identity into full view:… Continue reading Lack of Ethics: How Canada is Failing with COVID-19

More News from Protect Our Province BC

Post title - reinstate masks in public spaces
Protect Our Province BC, Safe Schools Coalition BC and BC School COVID Tracker are coming together to ask for mask protection in indoor public spaces, businesses, schools and on public transit in BC. The removal of BC’s mandated health protections has us concerned for the health and well-being of all British Columbians. “Now that masking… Continue reading Protect Our Province BC, Safe Schools Coalition BC and BC School COVID Tracker Issue Joint Press Release
translink masking open meeting title image
On March 11th, the British Columbia Public Health Officer, Dr. Bonnie Henry lifted the indoor mask mandate for most public places, with the main exception being healthcare settings.  TransLink immediately followed suit and lifted its own mask requirement, leaving commuters on  buses and trains with very few COVID-19 precautions. Unlike BC, Ontario and Quebec have… Continue reading Transit Users Ask Translink to Keep Mask Protections in Place.
Title image for blog April 2 - N95 masks and transmission
Share this: April 2, 2022  A Guest Post by Tim Henthorne, B.A.Sc., P. Eng Over the past two years, we have been flooded with opinions regarding the wearing of masks, all while trying to learn how to deal with the existential threat of COVID-19. Unfortunately, much confusion has come from Public Health itself with its… Continue reading N95 Masks & the Transmission of COVID-19